Ovarian Mature Cystic Teratoma Exhibiting Well-Differentiated Cerebellum in a 14-Year-Old Female

Domínguez-Rosado, Ismael; Michel, Joseph; Ortíz Hidalgo, Carlos Federico

doi:10.1007/s10024-004-7083-1

Ovarian Mature Cystic Teratoma Exhibiting Well-Differentiated Cerebellum in a 14-Year-Old Female

Journal

Pediatric and Developmental Pathology

ISSN

1093-5266

1615-5742

Date Issued

2005

Author(s)

Domínguez-Rosado, Ismael

Michel, Joseph

Ortíz Hidalgo, Carlos Federico

Facultad de Ciencias de la Salud - CampCM

Type

text::journal::journal article

DOI

10.1007/s10024-004-7083-1

URL

https://scripta.up.edu.mx/handle/20.500.12552/2505

Abstract

Ectodermal derivatives predominate in almost all cases of mature cystic teratoma. Organized neural tissue is a common finding, and, although glial cells predominate, well-organized cerebrum, cerebellum, and choroid plexus may be found [1]. We recently studied a case of a mature cystic teratoma that exhibited an area of mature, well-formed cerebellum. To the best of our knowledge, there have been 12 cases of cerebellar tissue within an ovarian teratoma reported in the literature, 4 of which correspond to immature cerebellar tissue with the presence of an Obersteiner external granular layer. Our case represents the youngest patient reported, with mature and well-differentiated cerebellar tissue within a mature cystic teratoma. © Pediatric and Developmental Pathology