HLA-DR alleles associated with skin warts induced by human papillomavirus infection

Background The skin wart is a benign proliferation of the skin and mucous, secondary to human papillomavirus (HPV) infection. Objectives The objective of this study is to determine gene frequencies of HLA-DR alleles in Mexican patients with skin warts and compare them with those present in ethnically matched healthy subjects. Methods Fifty-two patients with clinically and histologically confirmed skin warts from the Dermatology Outpatient Clinic, with results of high-resolution DNA typing for HLA-DR polymorphism.