Cervantes-Sánchez, Carlos R.Carlos R.Cervantes-SánchezOlaya, EnriqueEnriqueOlayaTestas, ManuelManuelTestasGarcia-López, NorbertoNorbertoGarcia-LópezCoste, GabrielGabrielCosteLuna, AdriánAdriánLunaKrötzsch, Fernando EdgarFernando EdgarKrötzsch2023-01-282023-01-282003https://scripta.up.edu.mx/handle/20.500.12552/252010.1016/S0022-4804(02)00099-9Background. Adhesion formation in the peritoneal cavity is the most common cause of intestinal obstruction and secondary female infertility. A great effort has been dedicated to reduce adhesion formation because of the associated morbidity and its complications. Materials and methods. This study was designed as a before-after comparative trial and included 14 rabbits, with a weight between 300 and 500 g. All rabbits were appendectomized and 1 month later laparotomized to assess adhesion formation. Rabbits were randomized into two groups, Group I (control group), with no intervention, and Group II (experimental group), treated with an intraperitoneal sponge of collagen-polyvinylpyrrolidone (Clg-PVP). The laparotomy procedure was repeated 1 month later for a new assessment of adhesion formation and histological evaluation by H-E and Masson staining.enResource Types::text::journal::journal article