Ramirez-Sandoval, Juan C.Juan C.Ramirez-SandovalDiener-Cabieses, PabloPabloDiener-CabiesesGutiérrez-Valle, FabiánFabiánGutiérrez-ValleLey-Tapia, SofíaSofíaLey-TapiaPastrana-Brandes, SantiagoSantiagoPastrana-BrandesGalindo, Pablo E.Pablo E.GalindoFagundo, ReynerioReynerioFagundoMoreno-Yañez, MauricioMauricioMoreno-YañezReza-Albarrán, Alfredo AdolfoAlfredo AdolfoReza-AlbarránCorrea-Rotter, RicardoRicardoCorrea-Rotter2022-11-242022-11-242022https://scripta.up.edu.mx/handle/20.500.12552/218110.1007/s11255-022-03170-zPurpose: Free calcium is the gold standard for diagnosis of calcium disorders, although calcium assessment is routinely performed by albumin-adjusted calcium. Our objective was to develop a novel-specific correction equation for free calcium employing serum total calcium and other analytes. Methods: Retrospective single-center cohort study. A new equation for free calcium assessment was formulated from data of hospitalized patients (n = 3481, measurements = 7157) and tested in a validation cohort (n = 3218, measurements = 6911). All measurements were performed simultaneously from the same blood draw. © International Urology and NephrologyenValidation of an equation for free calcium estimation: accuracy improves after adjustment for phosphate and CO2Resource Types::text::journal::journal article