DeRiemer, KathrynKathrynDeRiemerGarcía-García, LourdesLourdesGarcía-GarcíaBobadilla-del-Valle, MiriamMiriamBobadilla-del-VallePalacios-Martínez, ManuelManuelPalacios-MartínezMartínez-Gamboa, AreliAreliMartínez-GamboaSmall, Peter M.Peter M.SmallSifuentes-Osornio, JoséJoséSifuentes-Osornio2023-01-282023-01-282005https://scripta.up.edu.mx/handle/20.500.12552/250210.1016/S0140-6736(05)74812-1Background: Directly observed therapy (DOTS) is the main strategy for prevention and control of tuberculosis worldwide. However, its effect on tuberculosis transmission in populations with moderate rates of drug-resistant disease is not known. Methods: This population-based prospective study in southern Mexico between March, 1995, and February, 2000, was based on passive case finding and detection of acid-fast bacilli in sputum samples to diagnose pulmonary tuberculosis. We also used cultures, drug-susceptibility testing, bacterial genotyping, and monitoring of treatment outcomes. © The LancetResource Types::text::journal::journal article