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Author: search.filters.author.Alberú, JosefinaLanguage: search.filters.language.English

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    Extended major histocompatibility complex haplotypes, ancestry and acute kidney transplant rejection in Mexicans
    (2011-07)
    Riquelme Mc Loughlin, M. Constanza
    ;
    Granados, Julio
    ;
    Acuña-Alonzo, Víctor
    ;
    Telich, Eduardo
    ;
    Mancilla-Urrea, Eduardo
    Introduction. Extended major histocompatibility complex (MHC) haplotypes are associated with several autoimmune diseases, and these appear to depend on ancestry. Objective. To evaluate the association of extended MHC gene frequencies, ancestry, and acute rejection. Material and methods. 127 living kidney transplant recipients who underwent kidney transplantation in Mexico City between January 2004 and October 2007 with follow up until October 2008. The primary outcome was biopsy proven acute rejection. Ancestry was considered as either Amerindian or admixtures with Caucasian, African or Oriental genes. Allele and haplotype frequencies were estimated for HLA A, B and DR loci. Hardy Weinberg (HW) and delta values were analyzed to test for linkage disequilibrium (LD).© Revista de Investigación Clínica
    Scopus© Citations 2  36  2
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    A Report of the Lisbon Conference on the Care of the Kidney Transplant Recipient
    (2007)
    Abbud-Filho, Mario
    ;
    Adams, Patricia L.
    ;
    Alberú, Josefina
    ;
    Cardella, Carl
    ;
    Chapman, Jeremy
    An International Conference on the Care of the Kidney Transplant Recipient was convened in Lisbon, Portugal from February 2–4, 2006 under the auspices of the National Kidney Foundation and Kidney Disease: Improving Global Outcomes (KDIGO), and in cooperation with The Transplantation Society. Conference participants included over 100 experts and leaders in kidney transplantation, representing more than 40 countries from around the world, including participants from Africa, Asia, Australia, Europe, North American, and South America (Appendix). The goal of the conference was to develop recommendations to improve the outcomes of kidney transplant recipients worldwide with regard to the following basic medical issues: cardiovascular disease (Work Group I), cancer and infection (Work Group II), and anemia, bone disease, reproductive issues, growth and development (Work Group III). Work Groups I, II, and III addressed the preand posttransplant care of kidney transplant recipients by the following components: timelines of pre- and posttransplantation, immunosuppression, level of kidney allograft function, and burden of disease (prior history of dialysis or preemptive transplant and how that history affects outcome).
    Scopus© Citations 92  14  5