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Item type:Publication, Association between coping of the primary caregiver and the adolescent patient with cancer(Springer Science and Business Media, 2025) ;Villanueva Leonel, Jaramillo ;Rendón-Macías, Mario EnriqueRíos Covian, AnaBackground: Coping mechanisms help individuals face adversity, remain stable over time, and can be generalized to various circumstances. Two types are typically distinguished: the active style, aimed at resolving problems, and the passive style, focused on emotional regulation. We hypothesized that passive coping of the primary caregiver (hereafter, primary caregiver [PC]) would affect the adaptive coping of his or her adolescent child with cancer (hereafter, adolescent with cancer [AC]). Objective: To analyze coping styles in adolescents with cancer (ACs) and their primary caregivers (PCs). Materials and methods: This was an analytical cross-sectional study including 116 pairs of an adolescent with cancer (AC) and a primary caregiver (PC). The adolescents completed the Adolescent Coping Scale (ACS), applicable to those aged 9–17 years, while the caregivers completed the Coping Strategies Inventory (CSI). Results: 49% (57/116) of the pairs both used the active coping style, and 14% showed the passive style in both members. No agreement was found between the coping styles of the AC and PC (Kappa = 0.15, 95% confidence interval [CI]: 0.13–0.14, p = 0.13). The multivariate analysis explained 61% of the variance (Nagelkerke pseudo R2 = 0.61; likelihood ratio = 191.4; p = 0.003). Conclusions: Passive coping by the primary caregiver occurred with low frequency, and active coping was favored, similar to that of the adolescent with cancer. ©The authors ©Springer Science and Business Media © BMC Primary Care. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Persistent Vitamin D Deficiency in Pediatric Patients with Cystic Fibrosis(MDPI AG, 2025) ;Reyes-Apodaca, Magali ;Lezana-Fernández, José L. ;Vázquez Frias, Rodrigo ;Rendón-Macías, Mario EnriqueGonzález-Molina, AlineBackground/Objectives: Cystic fibrosis (CF) is a multisystem disease caused by CFTR gene variants, with a high prevalence of vitamin D (VitD) deficiency despite the supplementation and schedules specifically developed for this population. Lower VitD levels have been associated with an increased risk of respiratory infections and pulmonary exacerbations in CF, with some pilot studies indicating the potential benefits of supplementation during acute episodes. This study aimed to describe the occurrence of VitD deficiency according to the supplemented dose in pediatric patients with CF. Methods: A cross-sectional analytical study was conducted to assess serum VitD levels in a pediatric population with cystic fibrosis. Clinical and biochemical data were collected, along with information on VitD intake and pancreatic enzyme dosage at the time of evaluation. Results: A total of 48 patients were included in the study. Normal VitD levels were observed in 41.7% of the patients, insufficiency in 31.3%, and deficiency in 27%. The median VitD intake was 2050 IU. A statistically significant difference was observed in patients with a daily intake exceeding 2000 IU. Only 10% of patients achieved levels above 30 ng/mL with a lower dose. No statistically significant association was identified between the pancreatic enzyme dosage and vitamin D levels. Conclusions: Vitamin D deficiency/insufficiency is a persistent problem in the pediatric CF population; the interventions targeting factors associated with this condition are required to refine supplementation schedules. These findings underscore the need for personalized strategies to optimize vitamin D status in PwCF. Ideally, these strategies should consider all associated factors, including genetic variants; however, with limited resources, our results suggest that a daily dose of 2000 IU of vitamin D may represent a reasonable and effective starting point for supplementation. © The authors © MDPI . - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Beyond Clinical Signs: The Interplay Between Vagal Tone and Lethargic Behavior in Preterm Infants(Informa UK Limited, 2025); ;Catano-Cedillo, LizRendón-Macías, Mario EnriqueIn this cross-sectional, observational study, the association between lethargy and vagal tone was analyzed in thirteen low-risk preterm infants. Infants underwent behavioral assessment and vagal tone measurement indexed by high-frequency heart-rate variability (HF-HRV). A lower vagal tone cluster was associated with greater lethargy (p = .05), reduced handling (p = .003), excitability (p = .006), higher skin stress indicators (p = .13), and central nervous system stress indicators (p = .10) than cluster with a higher vagal tone cluster. A lower vagal tone could indicate autonomic nervous system dysregulation or immaturity, leading to neurobehavioral challenges, such as lethargy and further neurodevelopmental difficulties. ©The authors ©Informa UK Limited ©Developmental Neuropsychology.
