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Determining the Influence of Socioeconomic and Clinical Factors in Diabetes in the Mexican Population Using Machine Learning Techniques
(Springer Nature Switzerland, 2025)
Martínez Velasco, Antonieta Teodora
;
Terán-Bustamante, Antonia
Diabetes has a significant cost for health systems and the economy in general of countries, in addition to affecting the quality of life of people who suffer from it. Studying and analyzing the economic and clinical factors that trigger it allows us to identify the financial burden it represents and how policies and programs can be generated to support the prevention of this disease. This research aims to analyze the influence of socioeconomic and clinical factors on the Mexican population suffering from Diabetes. The analysis methods that are applied are the machine learning technique. The results in the Mexican population show that deaths from Diabetes occur more frequently in the population between 20 and 59 years of age. The factors related to housing-urbanization, specifically homes without piped water homes and houses with dirt floors, as well as people without the right to social security, are the critical factors that correlate with deaths caused by Diabetes: Hypertension, pneumonia, chronic respiratory diseases, coronary diseases, and influenza. ©The authors © Springer.
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Ibervillea sonorae (S. Watson) Green a potential resource of bioactive compounds: Systematic analysis of a Mexican plant used in traditional medicine
(Elsevier, 2025)
Angulo Molina, Aracely
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Cristofaro, Valeria di
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Pieles, Uwe
;
López Romero, Julio César
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Vidal Gutiérrez, Max
Ibervillea sonorae (S. Watson) Green (Cucurbitaceae) is a tuber succulent known as “wareke,” which grows in dry desert landscapes in northwestern Mexico and the southwestern United States. Indigenous tribes use I. sonorae as a remedy against cancer, inflammation, rheumatism, skin infections, and diabetes. The great popularity of wareke in traditional medicine has motivated various working groups to investigate its pharmacological properties. The antiproliferative, antitumoral, antifungal, hypoglycemic, antiinflammatory, antioxidant, and antimicrobial potential of this plant has been established. Chemical studies showed that I. sonorae is a potential resource of bioactive compounds, cucurbitacin-type triterpenoids, and phytosterols, the main secondary metabolites. The objective of this chapter is to systematically analyze the phytochemical knowledge of the plant (isolated and identified compounds), describe the biological activities of different extracts, isolated ingredients, and phytopreparations, and discuss their possible applications. ©The authors © 2025 Elsevier Inc.
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De-escalating treatment indications for patients who achieve metabolic goals
(Elsevier, 2024)
García-Ulloa, Ana Cristina
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Jaime-Casas, Salvador
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Rosado-Lozoya, Johanna S.
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Serrano-Pérez, Nancy H.
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Hernández-Juárez, Diana
Introduction: Robust evidence exists regarding initiation, intensification or modification of treatments. Recommendations to de-escalate therapy are lacking, specifically in diabetes. A successful treatment de-intensification reduces overtreatment, polypharmacy, and risk of adverse effects. Objective: To encompass current recommendations for deprescribing common drugs and create a consensus among health professionals. Methods: We reviewed four databases for deprescribing approaches published between 2010 and 2022. Articles were divided into different groups of drugs (for uric-acid, hypoglycemic, lipid-lowering, and psychotropic drugs).©Elsevier
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