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Language: search.filters.language.EnglishSubject: search.filters.subject.Granular cell tumor

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    Granular cell tumor (Abrikossoff tumor) of the thyroid gland
    (2009)
    Espinosa-de-Los-Monteros-Franco, Vladimir A.
    ;
    Martínez-Madrigal, Fernando
    ;
    Only 4 cases of granular cell tumor of the thyroid have been previously reported in the English literature. We report herein the fifth case of this uncommon neoplasm and the first one affecting a male patient. The tumor was well circumscribed and located to the left thyroid lobe, near the isthmus. Histologically, the tumor was composed of large, rounded, granular eosinophilic cells that were immunohistochemically positive for S-100, calretinin, and PGP9.5 and negative for cytokeratin AE1-3, TTF-1, and thyroglobulin. ©Annals of Diagnostic Pathology
    Scopus© Citations 14  10  2
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    Análisis histopatológico e inmunohistoquímico del tumor de células granulares. Estudios de 12 casos con una breve nota histórica
    (2019)
    ;
    Frías-Soria, Christian Lisette
    Introduction and objective: Granular cell tumour (GCT) is a benign neoplasm of neural/schwannian origin, usually presenting as a single asymptomatic lesion, mainly located in the dermis and subcutaneous tissue or submucosa, although multiple tumours may occur. Microscopically, GCTs are composed of large cells with abundant eosinophilic, granular cytoplasm arranged in sheets, nests, cords or trabeculae. Based on the cytological characteristics and the presence of necrosis, three types are recognized: benign, atypical and malignant. We aim to present the cytological and immunohistochemical characteristics of 12 granular cell tumours. Materials and methods: 12 cases of GCT were selected from the consultation files of one of the authors (COH) The paraffin embedded tissue was processed for immunostaining with S-100 protein, calretinin, CD68, α-inhibin, PGP9.5, CD57 (Leu7), CD63 (NKI / C3), Gap43 (growth-associated protein-43), SOX10, TFE-3 and Ki-67. © Revista Española de Patología
    Scopus© Citations 3  46  1