Schizophrenia is a psychiatric disorder characterized by neurocognitive symptoms and a generalized sensitivity to stress due to a neurodevelopment predisposition to this condition. We review some difficulties studying the relationship between subjacent vulnerability and stress response. These are mainly delimited to the selection of the samples and the scientific community's different conceptions of the clinical symptoms. With some of our work, we hold that the neurocognitive performance interacts positively with the allostatic load, mainly in the genetic high-risk group.
