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A Methodology Based on Deep Q-Learning/Genetic Algorithms for Optimizing COVID-19 Pandemic Government Actions

2020 , Miralles-Pechuán, Luis , Jiménez, Fernando , Ponce, Hiram , Martinez-Villaseñor, Lourdes

Whenever countries are threatened by a pandemic, as is the case with the COVID-19 virus, governments need help to take the right actions to safeguard public health as well as to mitigate the negative effects on the economy. A restrictive approach can seriously damage the economy. Conversely, a relaxed one may put at risk a high percentage of the population. Other investigations in this area are focused on modelling the spread of the virus or estimating the impact of the different measures on its propagation. However, in this paper, we propose a new methodology for helping governments in planning the phases to combat the pandemic based on their priorities. To this end, we implement the SEIR epidemiological model to represent the evolution of the COVID-19 virus on the population. To optimize the best sequences of actions governments can take, we propose a methodology with two approaches, one based on Deep Q-Learning and another one based on Genetic Algorithms. The sequences of actions (confinement, self-isolation, two-meter distance or not taking restrictions) are evaluated according to a reward system focused on meeting two objectives: firstly, getting few people infected so that hospitals are not overwhelmed, and secondly, avoiding taking drastic measures which could cause serious damage to the economy. The conducted experiments evaluate our methodology based on the accumulated rewards during the established period. The experiments also prove that it is a valid tool for governments to reduce the negative effects of a pandemic by optimizing the planning of the phases. According to our results, the approach based on Deep Q-Learning outperforms the one based on Genetic Algorithms. © 2020 ACM.

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An Explainable Tool to Support Age-related Macular Degeneration Diagnosis

2022 , Martinez-Villaseñor, Lourdes , Miralles-Pechuán, Luis , Ponce, Hiram , Martínez Velasco, Antonieta Teodora

Artificial intelligence and deep learning, in particu-lar, have gained large attention in the ophthalmology community due to the possibility of processing large amounts of data and dig-itized ocular images. Intelligent systems are developed to support the diagnosis and treatment of a number of ophthalmic diseases such as age-related macular degeneration (AMD), glaucoma and retinopathy of prematurity. Hence, explainability is necessary to gain trust and therefore the adoption of these critical decision support systems. Visual explanations have been proposed for AMD diagnosis only when optical coherence tomography (OCT) images are used, but interpretability using other inputs (i.e. data point-based features) for AMD diagnosis is rather limited. In this paper, we propose a practical tool to support AMD diagnosis based on Artificial Hydrocarbon Networks (AHN) with different kinds of input data such as demographic characteristics, features known as risk factors for AMD, and genetic variants obtained from DNA genotyping. The proposed explainer, namely eXplainable Artificial Hydrocarbon Networks (XAHN) is able to get global and local interpretations of the AHN model. An explainability assessment of the XAHN explainer was applied to clinicians for getting feedback from the tool. We consider the XAHN explainer tool will be beneficial to support expert clinicians in AMD diagnosis, especially where input data are not visual. © 2022 IEEE.

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Machine Learning Approach for Pre-Eclampsia Risk Factors Association

2018 , Martínez Velasco, Antonieta Teodora , Martinez-Villaseñor, Lourdes , Miralles-Pechuán, Luis

The preeclampsia/eclampsia syndrome is a multisystem disorder that usually includes cardiovascular changes, hematologic abnormalities, hepatic and renal impairment, and neurologic or cerebral manifestations. Preeclampsia (PE) is a clinical syndrome that afflicts 3–5% of pregnancies and it is a leading cause of maternal mortality, especially in developing countries. To understand in greater depth the preeclampsia/eclampsia syndrome, we applied some well-known Machine Learning (ML) techniques. ML has been successfully applied to medical research to improve the diagnosis and the prevention of complex diseases and syndromes. In our contribution, we have created a supervised model to predict if a patient suffers the disease. This model has been optimized by selecting the best features and by optimizing the threshold when predicting a class. We used these techniques to point out the most related features of the patients to the disease. Finally, we used interpretability techniques to extract and visualize through a decision tree the most relevant associations of the disease with the patients' features. © 2018 Association for Computing Machinery.

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Feature Selection Methods Evaluation for CTR Estimation

2016 , Miralles-Pechuán, Luis , Ponce, Hiram , Martinez-Villaseñor, Lourdes

The most widespread payment model in online advertising is Cost-per-click (CPC). In this model the advertisers pay each time that a user generates a click. In order to enhance the income of CPC Advertising Networks, it is necessary to give priority to the most profitable adverts. The most important factor in the profitability of an advert is Click-through-rate (CTR), which is the probability that a user generates a click in a given advert. In this paper we find which feature selection method between PCA, RFE, Gain ratio and NSGA-II is better suited, or if otherwise, the machine learning classification methods work best without any feature selection method. ©2016 IEE

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Machine learning method to establish the connection between age related macular degeneration and some genetic variations

2016 , Martínez Velasco, Antonieta Teodora , Zenteno, Juan Carlos , Martinez-Villaseñor, Lourdes , Miralles-Pechuán, Luis , Pérez Ortiz, Andric Christopher , Estrada Mena, Francisco Javier

Medicine research based in machine learning methods allows the improvement of diagnosis in complex diseases. Age related Macular Degeneration (AMD) is one of them. AMD is the leading cause of blindness in the world. It causes the 8.7% of blind people. A set of case and controls study could be developed by machine-learning methods to find the relation between Single Nucleotide Polymorphisms (SNPs) SNP_A, SNP_B, SNP_C and AMD. In this paper we present a machine-learning based analysis to determine the relation of three single nucleotide SNPs and the AMD disease. The SNPs SNP_B, SNP_C remained in the top four relevant features with ophthalmologic surgeries and bilateral cataract. We aim also to determine the best set of features for the classification process. © Springer International Publishing AG 2016.