Philosophy of Science, understood as a special philosophical discipline, was born only at the beginning of the twentieth century as part of the effort for overcoming the “foundational crisis” that had affected especially mathematics and physics. Therefore, it was conceived as an investigation about the features and reliability of scientific knowledge and for a few decades was deeply marked by the philosophical approach of logical empiricism. This cognitive point of view persisted also when, after Kuhn’s work, the attention focused on the scientific activity in order to understand scientific change and a sociological model replaced the view that empirical adequacy and logical consistency are the factors that determine the change of scientific theories. Ethical, social and political considerations regarding science ware considered inappropriate and potentially dangerous since they violate the alleged “neutrality of science” with respect to values. Nevertheless, the strict intertwining of science and technology in contemporary “technoscience” has produced a wide debate regarding the practical aspect of technoscientific activity that has the intrinsic features of a philosophical debate. Therefore, it is natural and advisable that the entire wealth of the philosophical disciplines (and not just logic, ontology, epistemology and philosophy of language) be called to contribute to the specific complex discourse of the Philosophy of Science.