The effect of cocoa, soy, oats and fish oil on metabolic syndrome in rats

Barrios-Ramos, Juan P.; Garduño-Siciliano, Leticia; Loredo Mendoza, María Lilia; Chamorro-Cevallos, German; Jaramillo-Flores, Maria E.

doi:10.1002/jsfa.5637

The effect of cocoa, soy, oats and fish oil on metabolic syndrome in rats

Journal

Journal of the Science of Food and Agriculture

ISSN

0022-5142

Date Issued

2012

Author(s)

Barrios-Ramos, Juan P.

Garduño-Siciliano, Leticia

Loredo Mendoza, María Lilia

Facultad de Ciencias de la Salud - CampCM

Chamorro-Cevallos, German

Facultad de Ciencias de la Salud - CampCM

Jaramillo-Flores, Maria E.

Type

text::journal::journal article

DOI

10.1002/jsfa.5637

URL

https://scripta.up.edu.mx/handle/20.500.12552/2391

Abstract

Background: The effect of functional foods alone or in combination (cocoa + soy + oats + fish oil) on hepatic damage in rats affected with metabolic syndrome was investigated. Results: Rats that were given cocoa showed a decrease in the levels of triglycerides (TGs) and glucose (63 and 32% respectively) as well as a decrease in blood pressure (15%). Animals fed with soy showed a reduction of 21% in total cholesterol, 15% in blood pressure and 44% in TGs, while feeding oats reduced the concentration of TGs by 53% (P < 0.5). Fish oil caused a reduction in TGs (56%) and glucose (26%). The effect on blood pressure was statistically significant for the groups supplemented with cocoa, soy, cocoa + oats and the total mix. The main finding was a reduction in liver steatosis in animals supplemented with cocoa + oats (from 30 to 4.7% steatosis). Cocoa or fish oil alone did not protect the liver from damage, while cocoa + fish oil did.