Revisión comparativa de dolor central post-ictus y otras causas de origen encefálico : fisiopatología y tratamiento

Central pain is a common consequence of diverse neurological diseases, such as Stroke, Multiple Sclerosis and Parkinson's disease. This review article focuses on the pathophysiology of central pain in these diseases as well as its management. The physiology of pain is briefly reviewed followed by a discussion of the physiopathology of post-stroke central pain and its pharmacological and non-pharmacological management. Subsequently, the article reviews and compares central pain caused by multiple sclerosis and Parkinson's disease regarding pathophysiology, clinical manifestations and treatment. In addition, new pharmacologic and non-pharmacologic strategies for the treatment of central pain caused by these diseases are described, such as deep brain stimulation and transcranial magnetic stimulation. © 2018 Instituto Nacional de Neurología y Neurocirugía.