Introduction: CKD Hotspots

Obrador, Gregorio; Levin, Adeera

doi:10.1016/j.semnephrol.2019.02.010

Introduction: CKD Hotspots

Journal

Seminars in Nephrology

ISSN

0270-9295

Date Issued

2019

Author(s)

Obrador, Gregorio

Facultad de Ciencias de la Salud - CampCM

Levin, Adeera

Type

text::journal::journal article

DOI

10.1016/j.semnephrol.2019.02.010

URL

https://scripta.up.edu.mx/handle/20.500.12552/2083

Abstract

CKD hotspots refer to countries, regions, communities, or ethnicities with a higher than average incidence of CKD. 1 Although noncommunicable diseases, such as diabetes and hypertension, are the leading causes of CKD in developed and in most developing countries, infections and CKD of unknown etiology (CKDu) are the most frequent causes in the majority of CKD hotspots. 2 , 3 The term CKDu has been used to describe CKD that is not attributable to any traditional risk factor, such as diabetes, hypertension, or human immunodeficiency virus. 4 Several potential causative factors of CKDu have been implicated, including genetic, developmental, environmental, occupational, and social factors. However, despite extensive research, the specific causes of CKDu remain unknown in most CKD hotspots. © Seminars in Nephrology