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Prevalencia de anticuerpos contra SARS-CoV-2 en pacientes con cáncer y trabajadores de la salud vacunados con dos dosis de BNT162b2 o AZD122. Análisis de propensión
Journal
Gaceta Médica de México
ISSN
0016-3813
Date Issued
2023
Author(s)
Villaseñor-Echavarri, Rodrigo
Rosa-Martínez, Daniel De la
Frías-Jiménez, Emmanuel
Martin-Onraet, Alexandra
Cruz-Cruz, Alonso
Herrera-Montalvo, Luis A.
Vilar-Compte, Diana
Type
Resource Types::text::journal::journal article
Abstract
Background: Vaccination is the most effective intervention for reducing the burden of SARS-CoV-2-related disease; however, gaps in knowledge regarding cancer patients (CPs) immune response persist. Objectives: To evaluate the humoral response (anti-S antibodies) in CPs and healthcare workers (HCWs) vaccinated with two doses of BNT162b2 or AZD122 vaccines. Material and methods: Polyspecific anti-SARS-CoV-2 spike protein (anti-S) antibodies were quantified, and a 1:1 propensity score was used to balance baseline characteristics. Multiple logistic regressions were carried out to evaluate the effect of humoral response-related variables.