In this study, a methodology that combines artificial neural networks and nonlinear hyperelastic finite element modeling to simulate the temperature-dependent stress response of elastomer solids is presented. The methodology is verified by a discrete model of a tensile test specimen, which is used to generate stress–strain pairs of existent experimental data. The proposed method is also tested with a benchmark problem of a rubber-like cylinder under compression. Three grades of an elastomer used for diverse engineering applications are used throughout the study. On this basis, three neural network architecture with 10 hidden neurons are implemented as constitutive models to reproduce the experimental data of the materials. The validation results show that the proposed methodology can reproduce tensile tests with an error of 5% of less than regarding experimental data for elastomers that present no yielding point. The benchmark problem results were at the range expected for the elastomer materials with no yielding, where it was possible to derive force temperature-dependent responses. These results suggest that the methodology helps the prediction of the material response when only material stress–strain curves at different temperatures exist. Therefore, the presented approach in this contribution helps to simulate the temperature-dependent stress responses of elastomeric solids with no defined yielding point.