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    Beyond Clinical Signs: The Interplay Between Vagal Tone and Lethargic Behavior in Preterm Infants
    (Informa UK Limited, 2025)
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    Catano-Cedillo, Liz
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    Rendón-Macías, Mario Enrique
    In this cross-sectional, observational study, the association between lethargy and vagal tone was analyzed in thirteen low-risk preterm infants. Infants underwent behavioral assessment and vagal tone measurement indexed by high-frequency heart-rate variability (HF-HRV). A lower vagal tone cluster was associated with greater lethargy (p = .05), reduced handling (p = .003), excitability (p = .006), higher skin stress indicators (p = .13), and central nervous system stress indicators (p = .10) than cluster with a higher vagal tone cluster. A lower vagal tone could indicate autonomic nervous system dysregulation or immaturity, leading to neurobehavioral challenges, such as lethargy and further neurodevelopmental difficulties. ©The authors ©Informa UK Limited ©Developmental Neuropsychology.
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    Comparación de síntomas de hiperactividad e inatención en adolescentes con y sin antecedentes de embarazo
    (2018)
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    Tafoya , Silvia A.
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    Meillon, Francisco
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    Poblano, Adrián
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    Ayala-Yáñez, Rodrigo
    Introduction: Teenage pregnancy has a negative impact both on mother's health and on her offspring quality life and development. In spite of its important social relevance, behavioral factors that can favor its occurrence have not been extensively explored. Objective: To compare symptoms of inattention and hyperactivity between adolescents with and without a history of pregnancy. Method: A sociodemographic record and the attention deficit hyperactivity disorder questionnaire (ADD) of the Neuropsi instrument were applied to 60 adolescents: 30 cases and 30 controls. The ADD was answered by the adolescents themselves, as well as by a close relative (parent or spouse) or by one of their teachers. Results: From the perspective of others (parents and teachers), adolescents with a history of pregnancy showed more symptoms of attention deficit and higher attention deficit and hyperactivity overall score (both p ≤ 0.01). In addition, ADD overall score was found to be associated with adolescent pregnancy (OR = 1.11, 95% CI = 1.01-1.24, p = 0.036). Conclusions: Symptoms of attention deficit and hyperactivity can represent another factor associated with teenage pregnancy. Copyright: © 2018 Secretaría de Salud
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    Differential fetal growth rates mediated by sociodemographic factors in Yucatan, Mexico: an epidemiological study
    (2022)
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    Azcorra, Hugo
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    Salvador-Ginez, Octavio
    Background: Fetal growth restriction (FGR) may be related to ethnicity. Additionally, ethnic groups experience adverse socioeconomic circumstances that increase FGR risk. However, the dearth of evidence of the interaction between socioeconomic factors and FGR highlights the need for additional research. Objective: To analyze the association between socioeconomic factors and FGR in Maya and non-Maya populations in Yucatan, Mexico. Methods: A total of 21,320 singleton births in 2017 in Yucatan were analyzed. The student’s t-test and the chi-square test were used to compare the means and proportions of maternal and perinatal variables between the FGR group and the birthweight appropriate for gestational age (AGA) group. Path analysis was performed to identify the direct and indirect effects of socioeconomic factors on FGR and mediators between predictors and FGR. © The Journal of Maternal-Fetal & Neonatal Medicine
    Scopus© Citations 1  9  1
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    The Interactive Effect of Positive Mental Health and Subjective Sleep Quality on Depressive Symptoms in High School Students
    (2018)
    Tafoya, Silvia A.
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    Objective/Background: The objective of this study was to observe the effect of positive mental health (PMH) and subjective sleep quality (SQ) on depressive symptoms in high school students. Participants: This cross-sectional study evaluated 2,186 students (55% female and 45% male) with a mean age of 16.8 years (SD ± 0.7) at 20 private high schools in Mexico City. Methods: An electronic survey was used, which included a questionnaire on sleep habits that is a Spanish-language adaptation of Rosenthal's Sleep-Wake Activity Inventory, the Pittsburgh Sleep Quality Index (PSQI), the Morningness-Eveningness Scale for Children and Adolescents (MESC), the combined scales to evaluate positive aspects of mental health, and the Patient Health Questionnaire (PHQ-9).
    Scopus© Citations 8  5  1
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    Infants prenatally exposed to SARS-CoV-2 show the absence of fidgety movements and are at higher risk for neurological disorders: A comparative study
    (2022)
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    Bobadilla, Liliana
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    Tafoya, Silvia A.
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    Gonzalez-Carpinteiro, Aline
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    Nava, Fernanda
    Congenital viral infections are believed to damage the developing neonatal brain. However, whether neonates exposed to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) show manifestations of such damage remains unclear. For neurodevelopment evaluation, general movement assessments have been shown to be effective in identifying early indicators of neurological dysfunction, including the absence of fidgety movements. This study compared the early motor repertoire by general movement assessment at three to five months of age in neonates who were or were not prenatally exposed to SARS-CoV-2 to determine whether infants prenatally exposed to SARS-CoV-2 are at risk of developing neurological disorders. Fifty-six infants, including 28 in the exposed group of mothers without vaccination who had no need for intensive care and likely had SARS-CoV-2 infection close to the time of pregnancy resolution and 28 infants in the nonexposed group, were videotaped to compare their detailed early motor repertoires, in which a motor optimality score-revised (MOS-R) was calculated using Prechtl’s method by using the chi-square or Mann–Whitney U tests. In the exposed group, 3 (11%) infants showed the absence of fidgety movements with a total MOS-R<14 points, and 3 (11%) other infants showed abnormal fidgety movements. Between groups, atypical body symmetry (p = 0.009) and MOS-R values were significantly lower (Z = -3.08, p = 0.002), with a large size effect (Cohen’s d = 0.97). The consequences of this new virus go beyond the health of the pregnant mother, and these consequences in some of the infants in the exposed group are likely not transitory because of the absence of fidgety movements between 3–5 months; thus, these babies are at increased risk of developing a serious neurological disorder.
    Scopus© Citations 27  21  2
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    Fetal growth restriction: From Polyvagal theory to developmental impairments?
    (2019)
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    Poblano, Adrián
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    Tafoya, Silvia A.
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    Ramírez-García, Luz Angélica
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    Casasola, Cesar
    Background The Polyvagal theory argues that behavioral modulation is a fundamental neurodevelopmental process that depends on autonomic regulation. Objective The present study aimed to assess sleep architecture in newborns with fetal growth restriction (FGR) using polysomnography as an indicator of Polyvagal theory. Methods We studied polysomnography recordings from 68 preterm infants, 34 with FGR and 34 born with appropriate growth for gestational age (AGA), who were matched according to the corrected age for prematurity (CA). Total sleep time, arousals, the percentage of quiet sleep, active sleep, indeterminate sleep, and heart rate were compared between the groups. Linear multiple regression analyses were used to evaluate polysomnography data for the FGR and AGA groups.
    Scopus© Citations 3  32  2
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    Effect of late-onset fetal growth restriction on organization of behavioral state in infants
    (2015)
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    Schnaas, Lourdes
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    Poblano, Adrián
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    Carrillo-Mora, Paul
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    Olivas-Peña, Efraín
    Background The aim of this study was to analyze whether late-onset fetal growth restriction (FGR) alters regulatory capability in infants, and whether this can be detected using both the neonatal behavior assessment scale (NBAS) and brainstem auditory-evoked potentials (BAEP). Methods The diagnosis of FGR was made on Doppler examination in the third trimester of pregnancy. NBAS and BAEP measurement were performed at 1 month of corrected postnatal age.
    Scopus© Citations 6  5  2
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    Habituation Alteration in Infants with Periventricular Echogenicity as an Indicator of Neurocognitive Impairment
    (2021)
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    Tafoya, Silvia A.
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    Ramírez-García, Luz Angélica
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    Poblano, Adrián
    Habituation difficulties may suggest neurocognitive impairment. Periventricular echogenicity (PVE) potentially causes subtle damage that poses neuropsychological risk. Habituation was evaluated through heart rate and behavioral states in infants at 36–37 weeks of corrected age between control and PVE groups. PVE infants showed early alertness and abrupt changes in behavioral states. However, the comparison group could better regulate their states. Heart rate was significantly high and remained unchanged in the PVE group but decreased in the control group. Alterations during the habituation paradigm in PVE infants could be early indicators of neuropsychological risk impairment. Scope of early habituation assessment is discussed. © 2021 Taylor & Francis Group, LLC.
      11  2
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    Skin to skin care and heart rate regulation
    (2015)
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    Perapoch, Joseph
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    Poblano, Adrián
    Dear Editor Recently we read the papers by Neu et al. and Mörelius et al. [1], [2]. Their research documented cortisol co-regulation between mothers and infants during skin to skin care (SSC). Even though both studies' results exhibited lower cortisol levels, in one study with marginal differences [1] and in the other, with significant differences [2] between a group of premature infants SSC treated, as compared to the standard care (SC) group, only Mörelius et al. found cortisol co-regulation at four months of age, as an index of neuro-endrocrine effect of SSC [2]. ©Early Human Development
    Scopus© Citations 1  15  1