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    Pediatric conjunctival melanoma: A comprehensive case report and literature review
    (Elsevier, 2024)
    Cantú-Soriano, Gonzalo N.
    ;
    Sánchez, N. G.
    ;
    Suárez-Reynoso, L.
    ;
    Padilla Rodríguez, Álvaro Lezid
    Purpose: This case report aims to present a rare instance of conjunctival melanoma in a 5-year-old patient and contribute to the limited body of knowledge on pediatric conjunctival melanoma. The purpose is to understand the characteristics, diagnosis, and management of this uncommon malignancy in young individuals. Observations: The case describes a 5-year-old female with a progressively growing pigmented conjunctival lesion. The lesion was observed to be located on the temporal conjunctiva of the right eye and displayed distinctive features, including feeder vessels. Imaging revealed specific dimensions of the lesion and ruled out deeper invasions. Histopathological examination revealed architectural and cytologic atypia, positive immunohistochemical staining for HMB-45, and a Ki67 proliferation index of 20 %, confirming the diagnosis of conjunctival melanoma. ©American Journal of Ophthalmology Case Reports.
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    Dilemas bioéticos y sus posibles soluciones en las unidades de terapia intensiva pediátrica del Distrito Federal (México)
    (Universidad de Chile, Centro Interdisciplinario de Estudios en Bioética, 2013)
    Caballero Velarde, María Cristina
    The process of decision making in pediatric intensive therapy units (PITU) is based on an ethical, legal and scientific framework, which generally is more complex that with adults and involves parents or tutors, thus, it must be solved carefully, with time and methodological precision. A survey was design for experts with anonymous and voluntary application, in a non institutional way, in which questions arise referring to bioethical dilemmas generated in PITU services and proceedings for their solution are proposed. Delphi method was used as instrument in two rounds. The most important results, among others, consisted in recognizing that all physician surveyed face in their unit ethical dilemmas, the most frequent being obstinacy in therapy in 32% cases, result linked to the difficulty to establish the diagnosis of terminal patient in 13% cases. To include bioethics topics and decision making with moral content in training professionals, as well as implementing assertive communication among health care team and families, and promoting adequate functioning of hospital bioethics committees with emergency consulting functions, are proposals which arise from the conclusions of this study.
    Scopus© Citations 2  18  2
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    COVID-19 and Fontan: bioethical analysis derived from the need for hospital reconversion
    (2022)
    Gómezchico-Velasco, Rebeca
    ;
    ;
    Salazar-Lizárraga, David
    ;
    Yáñez-Gutiérrez, Lucelli
    ;
    Márquez-González, Horacio
    Background: Among congenital heart diseases, those with univentricular physiology are the most severe with the lowest survival. Fontan surgery (FS) is the procedure of choice, as it bypasses the flow from the caval veins to the pulmonary circulation but requires close monitoring for late complications. The SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) pandemic caused nations to prioritize the availability of human and material health resources to benefit those infected. This study aimed to evaluate the clinical consequences of hospital reconversion due to the COVID-19 pandemic in a univentricular heart clinic for patients with FS from the bioethical perspective. Methods: We conducted an analytical cross-sectional study in a captive cohort of patients with FS treated in a tertiary hospital with conversion to COVID-19 patient care. The consequences of discontinuation of follow-up were recorded. Qualitative variables were expressed as frequencies and percentages, and quantitative variables as medians and interquartile ranges (p25-p75). Comparison between the two groups was performed with the χ2 test. ©Boletín Médico del Hospital Infantil de México
    Scopus© Citations 1  16  2