Synovial sarcoma of the tongue confirmed by molecular detection of the SYT-SSX2 fusion gene transcript

Villaroel-Salinas, Jaime; Campos-Martinez, Jesús; Ortíz Hidalgo, Carlos Federico

doi:10.1177/1066896911424897

Synovial sarcoma of the tongue confirmed by molecular detection of the SYT-SSX2 fusion gene transcript

Journal

International Journal of Surgical Pathology

ISSN

1066-8969

1940-2465

Date Issued

2011

Author(s)

Villaroel-Salinas, Jaime

Campos-Martinez, Jesús

Ortíz Hidalgo, Carlos Federico

Facultad de Ciencias de la Salud - CampCM

Type

text::journal::journal article

DOI

10.1177/1066896911424897

URL

https://scripta.up.edu.mx/handle/20.500.12552/2388

Abstract

Involvement of the tongue by a synovial sarcoma (SS) is an extremely rare event; there have only been 13 cases previously reported. The authors present herein a case of monophasic SS arising in the tongue in a 32-year-old woman. The neoplasm expressed cytokeratins AE1-3, OSCAR, and EMA as well as Bcl-2 and TLE1. Molecular analysis indicated that the patient tested positive for the SYT/SS2 fusion transcript. © International Journal of Surgical Pathology