Synovial sarcoma of the tongue confirmed by molecular detection of the SYT-SSX2 fusion gene transcript

Journal
International Journal of Surgical Pathology
ISSN
1066-8969
1940-2465
Date Issued
2011
Author(s)
Villaroel-Salinas, Jaime
Campos-Martinez, Jesús
Type
Resource Types::text::journal::journal article
DOI
URL
Abstract
Involvement of the tongue by a synovial sarcoma (SS) is an extremely rare event; there have only been 13 cases previously reported. The authors present herein a case of monophasic SS arising in the tongue in a 32-year-old woman. The neoplasm expressed cytokeratins AE1-3, OSCAR, and EMA as well as Bcl-2 and TLE1. Molecular analysis indicated that the patient tested positive for the SYT/SS2 fusion transcript. © International Journal of Surgical Pathology