Glomeruloid hemangiomas localized to the skin of the trunk with no clinical features of POEMS syndrome

Glomeruloid hemangioma is a rare cutaneous benign vascular tumor originally described in 1990 by Chan et al. 1 Clinically, it is characterized by the presence of derma nodular red-purple papules mainly localized to the thorax and upper limbs, and characteristically resembles the histological morphology of renal glomeruli.1 The presence of glomeruloid hemangiomas is considered a specific marker of polyneuropathy, organomegaly, endocrinopathy, M-protein, skin changes (POEMS) syndrome – also known as Crow–Fukase syndrome or Takatsuki’s disease – and it is usually, but not always related with multicentric Castleman’s disease.1–5 Only a small number of the vascular lesions found in POEMS syndrome have the appearance of glomeruloid hemangiomas. © International Journal of Dermatology