Ataxia, dysarthria and brainstem lesions in an elderly patient: a diagnostic challenge
Journal
European Journal of Internal Medicine
ISSN
0953-6205
Publisher
Elsevier BV
Date Issued
2025-08
Author(s)
Zermeño-Napolitano, Daniela
Villaseñor-Echavarri, Rodrigo
Salame Khouri, Latife
Type
text::journal::journal article
Abstract
Case: description: A 75-year-old Hispanic man presented with a 3-year history of frequent falls conditioned by gait instability and generalized weakness. His symptoms progressed with worsening of gait imbalance, dysarthria, and dysphagia to both solids and liquids. He was previously active and independent, with no relevant past medical history. Upon admission, he exhibited preserved higher mental functions. There were no limitations in eye movements, although saccadic intrusions and multidirectional nystagmus What is the diagnosis?: A diagnosis of Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS) syndrome was established based on the characteristic MRI findings and clinical presentation ©The authors ©European Journal of Internal Medicine ©Elsevier BV.
License
Acceso Restringido
How to cite
Zermeño-Napolitano, D., Villaseñor-Echavarri, R., & Khouri, L. S. (2025). Ataxia, dysarthria and brainstem lesions in an elderly patient: a diagnostic challenge. European Journal of Internal Medicine, 106493. https://doi.org/10.1016/j.ejim.2025.106493