Phimosis: A rare complication of immunotherapy with durvalumab

Vázquez-Lavista, Luis Gabriel; Llorente, Luis; Alatorre-Alexander, Jorge; Ramírez Muciño, José Arturo

doi:10.1016/j.eucr.2020.101350

Phimosis: A rare complication of immunotherapy with durvalumab

Journal

Urology Case Reports

ISSN

2214-4420

Date Issued

2020

Author(s)

Vázquez-Lavista, Luis Gabriel

Llorente, Luis

Alatorre-Alexander, Jorge

Type

Resource Types::text::journal::journal article

DOI

10.1016/j.eucr.2020.101350

URL

https://scripta.up.edu.mx/handle/20.500.12552/2123

Abstract

We present a case of a 69 year old man with phimosis associated with immunotherapy with durvalumab for metastatic non-small-cell lung cancer. The patient developed vitiligo like dermatosis after the induction dose of durvalumab, subsequent administration of the immunotherapy the patient developed a fibrous ring of the foreskin. Immune-mediated adverse reactions have been described after the use of durvalumab, but, to our knowledge, there are no reports of phimosis and vitiligo like reactions. © 2020 The Authors