Systemic complications of chronic kidney disease

Obrador, Gregorio; Pereira, Brian J. G.

doi:10.3810/pgm.2002.02.1115

Systemic complications of chronic kidney disease

Journal

Postgraduate Medicine

ISSN

0032-5481

1941-9260

Date Issued

2015

Author(s)

Pereira, Brian J. G.

Type

Resource Types::text::journal::journal article

DOI

10.3810/pgm.2002.02.1115

URL

https://scripta.up.edu.mx/handle/20.500.12552/3741

Abstract

The kidney plays a critical role in the maintenance of homeostasis. As kidney function diminishes, excretory, regulatory, and endocrine function is lost, and complications develop in essentially every organ system. Kidney failure is the last stage in the continuum of progressive CKD. Management of the complications associated with CKD mainly includes dietary counseling, adequate control of volume and blood pressure, and use of phosphate binders, calcitriol (Calcijex, Rocaltrol), and erythropoietin. Many of these complications can be prevented or attenuated with optimal CKD care, which involves early detection of progressive kidney disease, interventions to retard its progression, prevention of uremic complications, attenuation of comorbid conditions, adequate preparation for kidney replacement therapy, and timely initiation of dialysis (figure 2). Closer attention to CKD care is likely to be the key to improved outcomes among patients with kidney failure.