Effect of Intradialytic Oral Nutritional Supplementation with or without Exercise Improves Muscle Mass Quality and Physical Function in Hemodialysis Patients: A Pilot Study
Journal
Nutrients
ISSN
2072-6643
Date Issued
2022
Author(s)
Martin-Alemañy, Geovana
Pérez-Navarro, Monserrat
Wilund, Kenneth R.
García-Villalobos, Gloria
Gómez-Guerrero, Irma
Reyes-Caldelas, Miguel Angel
Espinosa-Cuevas, Angeles
Escobedo, Galileo
Medeiros, Mara
Bennett, Paul N.
Valdez-Ortiz, Rafael
Type
text::journal::journal article
Abstract
Background: Oral nutritional supplementation (ONS) with or without exercise (EX) could improve muscle mass (MM) in chronic kidney disease.
Methods: Patients were randomized into two groups: (1) ONS and (2) ONS + EX. Thigh muscle area (cm2) and intramuscular lipid content via attenuation were evaluated at baseline and 6 months with computed tomography (CT) to measure MM quantity and quality. Physical function was measured by six-minute walk test (6 MWT), gait speed, handgrip strength (HGS), and Time Up and Go test (TUG) at baseline and 3 and 6 months.
Methods: Patients were randomized into two groups: (1) ONS and (2) ONS + EX. Thigh muscle area (cm2) and intramuscular lipid content via attenuation were evaluated at baseline and 6 months with computed tomography (CT) to measure MM quantity and quality. Physical function was measured by six-minute walk test (6 MWT), gait speed, handgrip strength (HGS), and Time Up and Go test (TUG) at baseline and 3 and 6 months.