Myopericytoma in an unusual location
Journal
Dermatology Online Journal
ISSN
1087-2108
Date Issued
2018
Author(s)
Ruiz-Arriaga, Leon Felipe
Ramírez Terán, Ana Laura
Fonte-Avalos, Verónica
Toussaint-Caire, Sonia
Vega-Memije, Ma. Elisa
De Anda-Juárez, Mariana Catalina
Type
text::journal::journal article
Abstract
Myopericytoma is a soft-tissue tumor of perivascular cells (pericytes). It is slow-growing, usually asymptomatic, and generally benign, although a malignant variant has been described. The etiology is unknown, but it has been associated with local trauma. The most common location is on the distal extremities. Histologically, it is characterized by a well-circumscribed, non-encapsulated proliferation of spindle shaped cells similar to myofibroblasts with oval nuclei and eosinophilic cytoplasm, arranged in perivascular concentric rings. There are few mitoses and no necrosis is reported. The immunohistochemical analysis is positive for smooth muscle actin and negative or weakly positive for desmin. A low Ki-67 proliferation index is typical. Treatment is surgical excision with free margins. Recurrences after adequate excision are uncommon. We describe a 48-year-old woman with a myopericytoma in an unusual location (next to the inner corner of her left eye) who was treated with surgical excision; there has been no recurrence after 5 years of follow up. © 2018, Dermatology Online Journal. All rights reserved.