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    Item type:Publication,
    Pediatric conjunctival melanoma: A comprehensive case report and literature review
    (Elsevier, 2024)
    Cantú-Soriano, Gonzalo N.
    ;
    Sánchez, N. G.
    ;
    Suárez-Reynoso, L.
    ;
    Padilla Rodríguez, Álvaro Lezid
    Purpose: This case report aims to present a rare instance of conjunctival melanoma in a 5-year-old patient and contribute to the limited body of knowledge on pediatric conjunctival melanoma. The purpose is to understand the characteristics, diagnosis, and management of this uncommon malignancy in young individuals. Observations: The case describes a 5-year-old female with a progressively growing pigmented conjunctival lesion. The lesion was observed to be located on the temporal conjunctiva of the right eye and displayed distinctive features, including feeder vessels. Imaging revealed specific dimensions of the lesion and ruled out deeper invasions. Histopathological examination revealed architectural and cytologic atypia, positive immunohistochemical staining for HMB-45, and a Ki67 proliferation index of 20 %, confirming the diagnosis of conjunctival melanoma. ©American Journal of Ophthalmology Case Reports.
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    Cutaneous Angiomyolipoma—a distinct entity that should be separated from classic Angiomyolipoma: complete review of existing cases and defining fundamental features
    (2022)
    Sánchez, Natalia Gabriela
    ;
    Ávila Romay, Alfonsina Angelica
    ;
    Martínez Luna, Eduwiges
    ;
    Padilla Rodríguez, Álvaro Lezid
    Cutaneous angiomyolipoma is a rare mesenchymal tumor that is demographically, clinically, and immunohistochemically distinct from its renal and extrarenal counterparts. We present a case of cutaneous angiomyolipoma in the right retroauricular area of a 35-year-old male patient and provide a broad systematic review of the literature and the largest compilation of cutaneous angiomyolipomas reported to date. According to the findings presented in this review, we conclude that cutaneous angiomyolipoma should be completely separated from renal and extrarenal angiomyolipomas and therefore be considered a distinct entity in the classification of skin tumors. ©The authors, JMIR Dermatology
    Scopus© Citations 2  20  1
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    Apéndice triluminal septado: Una variante morfológica de septo con muscularis propria
    (2023)
    Sánchez, N.G.
    ;
    Estrada-Ortíz, F. A.
    ;
    Peñarrieta-Daher, A.A.
    ;
    Padilla Rodríguez, Álvaro Lezid
    Las malformaciones del apéndice son extremadamente raras y usualmente son un hallazgo incidental1. Los apéndices septados solamente se han descrito en una serie de casos que reportó 25 casos de septos conformados por submucosa, sin muscularis propria2. Presentamos el primer caso de apéndice septado con cada luz separada por septos con muscularis propria. ©Revista de Gastroenterología de México
      24  1
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    Intra-abdominal Follicular Dendritic Cell Sarcoma With Marked Pleomorphic Features and Aberrant Expression of Neuroendocrine Markers: Report of a Case With Immunohistochemical Analysis
    (2007)
    Padilla Rodríguez, Álvaro Lezid
    ;
    Bembassat, Miguel
    ;
    Lopez, Miguel
    ;
    Follicular dendritic cell sarcoma (FDCS) is a very rare malignant tumor arising most frequently in lymph nodes with only few reports of extranodal locations. We report the case of a 35-year-old man with a large retroperitoneal mass. Histologically the tumor was composed of highly pleomorphic cells exhibiting some uncommon features such as an epithelioid appearance, cystic spaces, and multinucleated cells with morphologic features of emperipolesis. Immunohistochemically the neoplastic cells were immunoreactive for CD21, CD23 and CD35. A previously unreported expression of neuroendocrine markers (Synaptophisyn and Neuron-Specific-Enolase) was present. Ultrastructurally no neuroendocrine secretory granules were detected. FDCS can mimic a wide variety of other malignant tumors, and a correct diagnosis requires exclusion of other neoplasms and immunohistochemical confirmation. © 2007 Lippincott Williams & Wilkins, Inc.
    Scopus© Citations 16  11  1
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    Synchronous Benign and Malignant Mesenchymal Breast Tumor
    (2007)
    Padilla Rodríguez, Álvaro Lezid
    ;
    Padilla-Villalta, Alfonso
    ;
    Arandia, Yanitza
    A 45-year-old woman presented with a 3-month history of right breast mass. Clinical examination revealed a firm mass in the right upper outer quadrant of the breast. Ultrasonography revealed a hypoechogenic circumscribed solid mass. An 11 cm-sized tumor was surgically removed. © The Breast Journal
    Scopus© Citations 1  9  1
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    Pure hibernoma of the breast: insights about its origins
    (2012)
    Padilla Rodríguez, Álvaro Lezid
    Hibernomas are rare benign tumors composed of cells reminiscent of brown adipose tissue. In the mammary gland, hibernomas are extraordinary rare, with only 4 cases reported previously. We report the fifth case in a 37-year-old woman who presented with a slowly growing mobile mass in her right breast. A 2.2 cm well-circumscribed lobulated mass was completely removed. The histopathologic analysis showed the full characteristics of the hibernoma. A review of the clinicopathologic features of hibernomas, its relation to brown adipose tissue in humans, and considerations about its histogenesis are made.
    Scopus© Citations 7  19  2