Now showing 1 - 10 of 978
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    Item type:Publication,
    Preface
    (Springer Science and Business Media Deutschland GmbH, 2026)
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    Item type:Publication,
    Mapping the Antibiofilm Peptide Space with Similarity Networks and Curated Negative Sets
    (American Chemical Society (ACS), 2025)
    Castillo-Mendieta, Kevin
    ;
    ;
    Márquez, Edgar A.
    ;
    García-Giménez, José Luis
    ;
    Antunes, Agostinho
    Biofilm-forming microorganisms pose a growing threat in clinical and industrial settings due to their tolerance to conventional antimicrobials. Antibiofilm peptides (ABFPs) offer a promising alternative, yet their discovery is challenging due to sequence diversity and complex mechanisms of action. We present the most comprehensive curated ABFP dataset to date and systematically compare it against two negative sets: quorum sensing peptides (QSPs) and random peptides (RPs). Classical statistical analyses combined with alignment-free similarity networks─Chemical Space Networks (CSNs) and Half-Space Proximal Networks (HSPNs)─identified compositional and physicochemical features that distinguish ABFPs from negative sets. Integration of quantitative biofilm inhibition (MBIC) and eradication (MBEC) data enhanced the resolution of meaningful patterns in the antibiofilm chemical space. Network analyses revealed conserved ABFP-enriched clusters with bioactivity data, distinctive motifs absent in negative sets, and central peptides with high topological importance that may serve as scaffolds for developing potent antimicrobials. QSPs and RPs, as biologically distinct comparators, served as robust filters refining ABFP signatures and reducing false positives. Projection onto the HSPN confirmed that ABFPs occupy a unique and well-defined region of sequence space. This integrative framework─combining curated datasets, compositional profiling, and network topology─provides a practical platform to accelerate ABFP discovery by identifying key features that can be incorporated into rule-based filters for prioritizing promising candidates. © 2025 The Authors. Published by American Chemical Society.
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    Multiobjective model to optimize charging station location for the decarbonization process in Mexico
    (2025)
    Ruiz Barajas, Francisco
    ;
    ;
    Adrian Ramirez‐Nafarrate
    ;
    Rosa G. González‐Ramírez
    <jats:title>Abstract</jats:title><jats:p>Electric vehicles (EVs) offer significant potential for advancing sustainable environmental goals. However, their widespread adoption has been concentrated in urban areas, raising challenges for interurban travel. In many countries, charging station networks are primarily located within cities, highlighting a key opportunity for expansion to support longer distance journeys. This article addresses the facility location problem for EV charging stations to enable interurban travel. We propose a multiobjective optimization model based on the flow refueling location model with three objectives: maximizing CO<jats:sub>2</jats:sub> emissions reduction, minimizing total costs, and reducing user charging time. The model is solved using an epsilon constraint approach, and Mexico's charging station network is used as a case study. Through computational experiments, various scenarios are evaluated, and a comparative analysis is performed between electric and internal combustion vehicles. Results show that deploying 20 strategically located charging stations could mitigate 3.1 million tons of CO<jats:sub>2</jats:sub>, requiring an investment of nearly USD 3.9 million.</jats:p>
      37
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    Optimización de proyectos bajo modelos de gestión
    (2013)
    Barajas Huerta, Jaaziel Daniel
      4
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    Item type:Publication,
    Cybernetic Insights on GenAI and Learning in Higher Education
    (IEEE, 2026) ;
    Vilalta-Perdomo, Eliseo
    The rapid diffusion of Generative Artificial Intelligence (GenAI) is reshaping learning conditions, not by introducing new activities but by reorganising existing feedback structures among students, teachers, and learning environments. This study adopts a cybernetic perspective to explore how Gen AI influences the recursive processes of enquiry, collaboration, and reflection. Drawing on the concepts of feedback, adaptation, and regulation, this paper frames GenAI as an active participant in learning systems, redistributing agency, and reshaping the rhythm of interaction. A methodological guide is proposed for constructing case studies across disciplines, combining documentary artefacts and participant accounts to map the cybernetic dynamics in practice. A case study of a Quality Management module illustrates how GenAI reconfigures individual reflection, group collaboration, and assessment practices. This study contributes to cybernetic learning theory by showing how GenAI affects agency and feedback structures, and by providing a framework for designing ethical GenAI learning environments. This study acknowledges the limitations that future studies must address to examine student learning outcomes. The paper concludes by highlighting the research question: How does Gen AI reshape learning as a recursive cybernetic process? Scholars are invited to explore this in their own contexts in future studies. © The authors © IEEE.
      2
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    Sistema de tele operación de robots móviles omnidireccionales con emulación háptica de los sentidos de la vista y el oído
    (2010)
    Aguilera Sánchez, José Antonio
    ;
    Varona, Jorge
    Maestría en Ciencias - Tesis presentada en UP Aguascalientes
      3
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    El in-house bank de Coca-Cola Femsa
    (2015)
    Rodríguez Alva, Héctor
    ;
    Berumen-Glinz, Lorena Alexandra
    ;
    Campus Ciudad de México
    La administración de la tesorería se encarga de la administración de la liquidez de la compañía a fin de garantizar que los fondos necesarios se encuentren en el lugar, la divisa y el momento adecuados, manteniendo para ello relaciones oportunas con las entidades correspondientes, procurando optimizar los ciclos de cobro y pago, minimizando los fondos ociosos todo ello con un nivel de riesgo conocido y aceptado ... El In–House Bank es una herramienta poderosa para centralizar las actividades financieras del grupo y los riesgos inherentes a ellas, y añade un gran valor a la organización. Libera de operaciones locales de la administración del efectivo y cambio de divisas, reduce los gastos por interés y las comisiones bancarias del grupo, minimiza el efectivo ocioso y centraliza la administración a la exposición al riesgo cambiario. El In–House Bank debe operar como una entidad legal por separado, controlado por la tesorería del grupo ... Para propósitos prácticos, entidades legales individuales, subsidiarias y compañías operativas pueden interactuar con un In – House Bank como si fuera una institución financiera externa. El In – House Bank provee cuentas bancarias a cada subsidiaria, administra la conciliación de las transacciones intercompañía y provee un estado de cuenta como confirmación de los movimientos de dichas cuentas, del mismo modo que un banco externo lo haría .
      8  17
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    La enseñanza del cálculo a nivel medio superior
    (2004)
    Murillo Lopez, Francisco Jacobo
    ;
    Dávalos Orozco, Óscar
    Maestría en Enseñanza de las Matemáticas - Tesis presentada en UP Aguascalientes
      7
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    Plan estratégico de desarrollo de "Quesería Gutiérrez"
    (2021-10)
    Martínez Gutiérrez, Moisés
    En México, el consumo de queso es elevado, esto se debe a la gran variedad de quesos que tenemos actualmente en el país tales como el panela, añejo, Oaxaca, Cotija, asadero, chihuahua, etc. Su uso está en la mayoría de los platillos mexicanos típicos, como quesadillas, sopes, tostadas o enchiladas. Tan sólo el consumo de queso nacional es de más de 400 mil toneladas, de manera que los mexicanos consumimos actualmente entre 2.1 y hasta 6 kilos de queso al año. Sus estilos y sabores son resultado de diferentes tipos de leche, variaciones en el tiempo de curación y diversos tratamientos en su proceso. Se estima que en el mundo hay más de 2,000 tipos de quesos.
      3  3
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    Plan de desarrollo e introducción de productos innovadores al mercado : electrolizadores
    (2012)
    Orozco Mancera, Adrián
    ;
    Rodríguez González, Ernesto Leonides
      3