Now showing 1 - 10 of 73
  • Some of the metrics are blocked by your 
    Item type:Publication,
    Sarcoma histiocítico. Criterios diagnósticos histopatológicos e inmunohistoquímicos y sus diagnósticos diferenciales
    (2011)
    García-Gutiérrez, Mónica
    ;
    Histiocytic sarcoma (HS) is a rare malignant tumor, originating from bone marrow-derived myeloid stem cells, showing morphologic and immunophenotipic evidence of mature tissue histiocytes (macrophages). HS arises in lymph nodes and extranodal sites such as skin, soft tissues and particularly the gastrointestinal tract, often presenting with clinically advanced disease and pursuing and aggressive clinical course. The diagnosis of HS relies predominantly on the immunohistochemical features of the histiocytic lineage, and the exclusion of large cell lymphoma and other poorly differentiated large cell malignancies such as, carcinomas and melanomas.© Gaceta Mexicana de Oncología
      1  8
  • Some of the metrics are blocked by your 
    Item type:Publication,
    Mujer de 33 años de edad con leve dolor toracoabdominal derecho de seis años de evolución, súbitamente agudizado
    (2011)
    Cárdenas-Escudero, Mara A.
    ;
    Shuchleib-Chaba, Samuel
    ;
    Muruchi-Garrón, Germán Walter
    ;
    León-Bojorge, Beatriz de
    ;
    We present a case of a benign hybrid nerve sheath tumor showing features of both cellular schwannoma and perineurioma. The patient was a 33 year-old female who presented with a 6 month history of pain in the thorax-lumbar region. Axial CT and MIR images showed and homogeneously enhancing solid oval mass involving the left paravertebra region in contact with the vertebral foramina T9-T11. Morphologically the tumor presented a well formed capsule and showed a uniform highly spindle cell proliferation. The spindle cells were arranged in whorls and intersecting fascicles with focal intervening sclerosis and relatively uniform cellularity with a prominent perivascular lymphocytic infiltrate. No cytological atypia, necrosis or mitoses were present. A second cell component was present composed of spindle-shaped cells with inconspicuous bipolar, pale, eosinophilic cytoplasm with oval nuclei. By immunohistochemistry there was a diffuse staining for S-100, and the elongated bipolar cells were EMA, Glut-1 and Claudin-1. To our knowledge this is the first reported case of a hybrid cellular schwannoma/perineurioma. ©Gaceta Médica de México
      2  9
  • Some of the metrics are blocked by your 
    Item type:Publication,
    History of Leukemia, Revisited
    (Springer Science and Business Media LLC, 2025)
    Purpose of the Review: Provide a general historical overview of leukemia, emphasizing the early discoveries that led to its characterization. Recent Findings: Leukemia recognition began in the late 19th century with the advent of the microscope. Leeuwenhoek and Swammerdam described erythrocytes, while Lieutaud first observed globuli albicantes, later identified as lymphocytes by Hewson. Early case studies by Velpeau, Donné, Bennett, Craigie, Virchow, and Fuller suggested that leukocytosis could occur without infection. Virchow coined the term “leukemia,” while Bennett proposed “leucocythemia.” Neumann identified the bone marrow as the source of blood cells and leukemia, coining the term “myelogenous leukemia,” and Ehrlich classified leukemia into myeloid and lymphoid types. In 1914, Boveri linked chromosomal abnormalities to cancer, and in 1960, Nowell and Hungerford discovered the Philadelphia chromosome. The use of mustard gas in WWI led to the development of chemotherapy drugs like chlorambucil and busulfan. The Human Genome Project further advanced leukemia diagnosis and treatment. Summary: Leukemia, like many diseases, has evolved due to changes in causative factors such as viruses, bacteria, and genetic mutations, which have impacted its pathogenesis and treatment. It will undoubtedly continue to evolve, with new scientists working towards a cure for this devastating disease. ©The author ©Current Oncology Reports ©Springer Science and Business Media LLC.
      28
  • Some of the metrics are blocked by your 
    Item type:Publication,
    Linfoma anaplásico de células grandes : estudio clínico-patológico e inmunohistoquímica de 20 casos clasificados de acuerdo a la revisión de la Organización Mundial de la Salud de neoplasias linfoides de 2016
    (2022)
    Sevilla Lizcano, Diana Brisa
    ;
    Anaplastic large cell lymphoma (ALCL) is a type of non-Hodgkin lymphoma composed of CD30-positive neoplastic cells. The 2016 revision of the WHO classification of lymphoid neoplasms includes anaplastic lymphoma kinase (ALK) positive, ALK negative and breast implant associated ALCL. ALCL have distinct clinical and prognostic features between positive and negative cases. ALK-1 positive cases mostly occur in the first three decades of life while patients with ALK-1 negative are older. ALCL exhibit a very broad range of cytology appearances that include common pattern, lymphohistiocytic pattern, small-cell pattern, Hodgkin-like pattern and composite pattern. By definition, ALCL show strong CD30 staining on the cell membrane and in the Golgi region and the majority are epithelial membrane antigen positive, express one or more T-cell or Natural Killer antigens and are constantly negative for Epstein-Barr virus. We present the clinicopathologic and immunohistochemical analysis of 20 cases of ALCL studied at a single institution, classified according to the 2016 revision of lymphoid neoplasms. Nine cases were ALK-1 positive, ten ALK-1 negative, and one case as a breast implant associated ALCL ALK-1 negative. © 2017 Sociedad Mexicana de Oncología.
      2  10Scopus© Citations 1
  • Some of the metrics are blocked by your 
    Item type:Publication,
    El profesor y la costurera: Un episodio de la vida de Jacob Henle
    Jacob Henle was a great German anatomist and one of the most important histologists of all times. One of the most commonly used eponymous terms in renal histology is the loop of Henle, but many other anatomical and pathological findings are associated with his name. During his stay in Zurich he fell in love with Elise Egolff who worked as a maid and seamstress in the house of one of his friends. No one could ever imagine how the wide social chasm that separated the servant-girl and the professor could be bridged. Henle arranged for his sister Marie to educate Elise and give her social polish. In a short time Elise was transformed into a lady of the world. A year and a half later Jacob and Elise were married. This episode inspired the novelist Auerbach to write the novel “The Professor’s Wife”, and the play “Pygmalion” by George B Shaw. (Gac Med Mex. 2015;151:819-27). © Gaceta Médica de México.
      2  9
  • Some of the metrics are blocked by your 
    Item type:Publication,
    Small-Cell Plasmacytoma With Prominent Myxoid Stroma Mimicking a Soft-Tissue Neoplasm
    (2009)
    Lara-Torres, César Octavio
    ;
    Gómez-Plata, Eduardo
    ;
    In the majority of cases, histological diagnosis of plasma cell tumor can be made without difficulty; however, a proportion of them can represent a diagnostic challenge due to the wide spectrum of phenotypes that neoplastic plasma cells may exhibit. Numerous cytological and architectural variants have been well documented. Cytological, plasma cell tumors may show small, cleaved, multilobated, monocytoid, pleomorphic, histiocytoid, oncocytic, or clear cells. © International Journal of Surgical Pathology
      2Scopus© Citations 2  12
  • Some of the metrics are blocked by your 
    Item type:Publication,
    Expresión de CD-34 en el elastofibroma. Estudio clinicopatológico, histoquímico e inmunohistoquímico de cuatro casos
    (1999-01)
    Ruelas-Villavicencio, Ana Lilia
    ;
    Aponte Paredes, Paola Susana
    ;
    Objetivo. Explorar la expresión imunohistoquímica de células en casos de elastofibroma y evaluar cuatro técnicas histoquímicas para fibras elásticas. Material y métodos. Se obtuvieron cuatro elastofibromas de los archivos del departamento de patología del Hospital ABC. Todos los pacientes fueron mujeres cuyas lesiones se encontraron en la región subescapular. Se realizó inmunohistoquímica para CD34, actina, desmina, vimentina, proteína S-100 y bcl-2 y se evaluaron cuatro métodos para fibras elásticas (Verhoff, Gallego, Reyes-Mota y Russel-Movat). Resultados. En los cuatro casos habían numerosos miofibroblastos (positivos a la vimentina/actina/desmina). Además encontramos células dendríticas distribuidas irregularmente, positivas al CD34. Las tinciones de Verhoff y Reyes-Mota son las que mejor resaltan el componente elástico. El método de Russel-Movat es útil para distinguir diferentes componentes de tejido conectivo. Conclusión. Las células del elastofibroma originalmente se consideraron fibroblastos. La presencia de vimentina/actina/desmina sugiere que existe una población de miofibroblastos. Describimos por primera vez, células fusiformes y dendríticas, positivas al CD34 (QBend/10) distribuidas irregularmente en toda la lesión. Estas células pueden ser población reactiva de células del ®sistema dendrítico dérmico¼. No encontramos inmunorreactividad para bcl-2 en las células fusiformes y dendríticas © Revista de Investigación Clínica
      2Scopus© Citations 6  11
  • Some of the metrics are blocked by your 
    Item type:Publication,
    Carcinoma epidermoide orofaríngeo metastásico en ganglios linfáticos cervicales asociado a los subtipos 16 y 45 del virus del papiloma humano (VPH). estudio clínico, morfológico y molecular de dos casos
    (2013)
    Soria-Céspedes, Danny
    ;
    Canchola Aguilar, Guadalupe
    ;
    Lara-Torres, César Octavio
    ;
    Sánchez-Marle, Juan Felipe
    ;
    Hernández-Peña, Roberto Enrique
    Human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma has been identified as a distinct entity within squamous cell carcinoma of the head and neck. In contrast to carcinomas associated with alcohol and/or tobacco, this subtype occurs at younger age, with frequent absence of classic risk factors, correlation with oral sexual habits, strong predilection for the palatial tonsils and the base of the tongue (lingual tonsils), basaloid or lymphoepithelial differentiation, higher degree of radiosensitivity, and overall better survival. We report two cases of lymph node, metastatic, poorly differentiated squamous cell carcinoma that were positive by immunohistochemistry for p16 with detection of HPV-16 and HPV-45 by PCR. (Gac Med Mex. 2013;149:673-9) © Gaceta Médica de México
      1  27
  • Some of the metrics are blocked by your 
    Item type:Publication,
    Enfermedad de Castleman. Análisis histopatológico e inmunohistoquímico de treinta y nueve casos
    (2017)
    Brisa Sevilla-Lizcano, Diana
    ;
    Frias-Soria, Christian Lizette
    ;
    Introduction: Castleman disease (CD) is a rare lymphoproliferative that comprises two distinct clinical subtypes (unicentric and multicentric) and has two basic histopathology patterns that are hyaline-vascular (HV) and plasma-cell (PC) type. Some cases of multicentric PC disease are associated with HHV-8 infection. Objective: To present the histopathologic and immunohistochemical characteristics of 39 cases of CD. Methods: A review of cases with the diagnosis CD from the files of the Department of Pathology of the ABC Medical Centre in Mexico City was performed. Thirty-nine cases of CD were identified, and a detailed paraffin immunophenotypic study of 9 of them was completed using desmin, cytokeratin OSCAR (CO) and Epidermal growth factor receptor (EGFR), to evaluate the dendritic cell population. ©Gaceta Médica de México.
      2  10Scopus© Citations 9
  • Some of the metrics are blocked by your 
    Item type:Publication,
    Hematoxylin: Mesoamerica's Gift to Histopathology. Palo de Campeche (Logwood Tree), Pirates' Most Desired Treasure, and Irreplaceable Tissue Stain
    (2019) ;
    Pina-Oviedo, Sergio
    Hematoxylin is a basic dye derived from the heartwood of Palo de Campeche ( Haematoxylum campechianum), the logwood tree native to Mexico and Central America. Haematoxylum means "bloodwood" in reference to its dark-red heartwood and campechianum refers to its site of origin, the coastal city of Campeche on the Yucatan Peninsula, Mexico. Hematoxylin is colorless but it turns into the color dye hematein after oxidation (ripening). The dyeing property of logwood was well-known to the natives of the Yucatan Peninsula before the arrival of the Spaniards who brought it to Europe shortly after the discovery of the Americas. An important trade soon developed related to growing and preparing hematoxylin for dyeing fabrics. Pirates discovered that one shipload of logwood was equivalent to a year's value from any other cargo, and by 1563, more than 400 pirate vessels wandered the Atlantic Ocean and attacked Spanish galleons transporting gold, silver, and logwood from the Americas to Europe. Hematoxylin and eosin is a staining method that dates back to the late 19th century. In 1865 and 1891, Böhmer and Meyer, respectively, first used hematoxylin in combination with a mordant (alum). Later, with the use of anilines by Ehrlich, the repertoire of stains expanded rapidly resulting in the microscopic descriptions of multiple diseases that were defined by their stainable features. Today hematoxylin, along with eosin, remains the most popular stain in histology.©International Journal of Surgical Pathology
      2  7Scopus© Citations 34